Nicolas Baton, who was picked up as one of the pieces in the trade that sent James Harden to the Los Angeles Clippers, scored 11 points on 4-for-5 shooting in his Sixers debut.
Kyle Kuzma scored 28 points for Washington, and Jordan Poole had 23. The Wizards have lost four straight to fall to 1-5.
Washington turned the ball over 19 times, many of which turned into transition points against an offense that moved quickly up the floor most of the night.
Philadelphia 51 for 91 from the floor and 32 of 36 from the foul line.
Up next
Wizards: Travel to Charlotte to begin a home-and-home against the Hornets on Wednesday.
76ers: Host Boston on Wednesday night in first meeting since the Celtics’ win in Game 7 of last year’s Eastern Conference semifinals.